COMPLEMENT FIXATION WITH LECITHIN AS ANTIGEN IN PELLAGRA

Complement Fixation in Kala-Azar with the WKK Antigen

In our present issue we publish two articles in which the value of a complement-fixation test in early diagnosis of kala-azar is stressed. The antigen used is that of Witebsky, Klingenstein and Kuhn prepared from the tubercle bacillus, and originally intended for complement-fixation tests in tuberculosis. In tuberculosis, however, the results are very poor. Work in South America, however, revea...

Studies on the effect of variation of concentration and origin of lecithin (natural and synthetic) in cardiolipin complement-fixation antigen.

The significance of the relationship between the three components of cardiolipin complementfixation antigen, viz. cardiolipin, natural lecithin, and cholesterol, was first studied by Maltaner and Maltaner (1945) in experiments with syphilitic pooled rabbit or human sera. Suitable sensitivity with regard to the routine sero-diagnosis of syphilis was obtained with the antigen formula: Cardiolipin...

The coccidioidal complement fixation and immunodiffusion-complement fixation antigen is a chitinase.

Culture filtrates and autolysates of Coccidioides immitis have provided suitable crude antigens for the serodiagnosis and prognosis of coccidioidomycosis. One of these, a heat-labile antigen which participates in the immunodiffusion reaction corresponding to the complement fixation reaction (IDCF), has been characterized as a 110-kDa native protein that, when subjected to reducing conditions an...

Indirect Complement Fixation in Foot-and-Mouth Disease

Complement-Fixation Technique: II. THE TITRATION OF WASSERMANN ANTIGEN.

After material has been produced for use as an antigen in a complement fixation test it is necessary to find out if the finished product has any complement-fixing ability in the presence of a serum containing a suitable antibody. Moreover, the proposed antigen must not have any undue anticomplementary property, and the " gap" between its anticomplementary titre and its complement fixing titre m...